Thursday, September 20, 2012

How Sufferers Of Autoimmune Disorders Can Benefit From Liposomal Clodronate

By Ava McCormick


The immune system may be boosted by some drugs. But whenever necessary, it may also be suppressed. One such drug is called Liposomal Clodronate. It's something that those who are suffering from autoimmune disorders may benefit from.

Prepared in the laboratory, the product is administered through injection. Currently, there are only a few pharmaceutical companies manufacturing it. Many studies that aim to establish its full potential are still ongoing.

What it does is suppress the inappropriate action of the immune system when necessary. It's not always that this body's defense mechanism works to a person's advantage. Invading microorganisms such as toxins, bacteria, viruses and parasites should be the primary target. However, for unknown reasons, it sometimes turns its attention on the body itself.

When such happens, an autoimmune disorder takes place. The person's defenses begin to turn their attention on the self, such as the cells and tissues. One example is joint swelling, something that brings pain to the afflicted individual. It is not unlikely for someone to suffer from different kinds of autoimmune disorder at one time.

The vital organs may also be the ones targeted, and this can be a life-threatening situation. Their proper functioning may be compromised when the tissues that make them up are attacked and destroyed. Without the ability to distinguish the self from the enemies, simply imagine what could happen to the person if the liver or kidneys became the purported enemies.

Some of those responsible for various autoimmune disorders are phagocytes such as macrophages and monocytes. These types of white blood cells are role players in the immune system. They work by swallowing up perceived enemies and destroying them through digestion. The natural defenses are working as expected if their attention is focused on invading microorganisms.

However, it's a completely different story when it turns to the body itself. There is a long list of various known autoimmune disorders. By suppressing the activity of the immune response, an afflicted individual can see positive results.

This is when the drug comes very helpful. When injected into the body, naturally phagocytes will spring into action and try to contain the substance thinking that they are enemies. Once engulfed, toxins will be released, causing the demise of the attacking cells. Through this, the amount of phagocytes may be reduced, allowing for the weakening of the immune response.

Those with all sorts of autoimmune disorders are not the only ones who can benefit from such drug. It can also have positive effects on those who are undergoing organ transplant. Why the body rejects a new organ at times is because of the immune system itself. By suppressing its action using the drug, a more favorable outcome may be expected.

It is estimated that 1 out of 12 people will have some form of autoimmune disease. Liposomal Clodronate can prove to be beneficial for those who are suffering from such. To date, scientists are still trying to find out more information about the drug so that its full potential may be harnessed against all sorts of conditions related to an inappropriate immune response.




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